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Home / HP / Hard Drives / HP 857648-S21

HP 857648-S21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC Helium 512e HDD

Part Number: 857648-S21     Brand: HP
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HP 857648-S21 Product Specs

▲
Brand
HP
Capacity
10TB
Hot-Swappable
Yes
Spindle Speed
7.2K
Carrier Type
Smart Carrier (SC)
Interface Type
SATA
Data Transfer Rate
6Gb/s
Workload
MidLine (MDL)
Sector Size
512e
Form Factor
3.5" LFF
HPE Server Generations
Gen 9/Gen 8/Gen 10

This HP Hard Drive 857648-S21 is compatible with these HP Servers

▲
ProLiant DL20
ProLiant DL320
ProLiant DL325
ProLiant DL345
ProLiant DL360
ProLiant DL380
ProLiant DL385
ProLiant DL388
Proliant BL460c
Proliant DL120
Proliant DL160
Proliant DL180
Proliant DL20
Proliant DL380
Proliant DL385
Proliant DL388
Proliant DL60
Proliant DL80
Proliant ML110
Proliant ML150
Proliant ML30
Proliant ML310
Proliant ML350
Proliant ML350e
Proliant XL170r
Proliant XL190r

HP 857648-S21 Description

▼

The HP 857648-S21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC Helium 512e HDD is a high-capacity hard drive designed for enterprise-grade storage solutions. Ideal for data centers and businesses requiring reliable and scalable storage, this drive offers seamless compatibility with a wide range of HPE ProLiant server models including ProLiant DX, DL, ML, SL, BL, XL, and CL series. Whether you are upgrading your existing infrastructure or building a new server environment, this HDD provides robust performance and efficient data handling for demanding workloads.

This hard drive is engineered to meet the needs of MidLine (MDL) workloads, making it suitable for applications such as backup, archiving, and general-purpose storage. Its helium-filled design reduces friction and power consumption while enhancing reliability. The hot-swappable feature allows easy replacement or upgrades without downtime, ensuring continuous operation in critical environments.

Key specifications of the HP 857648-S21 highlight its impressive capacity and performance features:

  • Brand: HP
  • Capacity: 10TB
  • Hot-Swappable: Yes, for easy maintenance
  • Spindle Speed: 7,200 RPM, balancing speed and power efficiency
  • Carrier Type: Smart Carrier (SC) for secure and convenient installation
  • Interface Type: SATA with a data transfer rate of 6Gb/s
  • Workload: MidLine (MDL), optimized for moderate-intensity applications
  • Sector Size: 512e, supporting enhanced compatibility
  • Form Factor: 3.5" Large Form Factor (LFF)
  • HPE Server Generations Compatibility: Gen 8, Gen 9, and Gen 10

For maintenance and replacement purposes, the following spare part numbers are associated with this hard drive:

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ⓘ We found 14 subs for the HP 857648-S21
100% Match
HP 857643-002 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
100% Match
HP 857650-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
100% Match
HP 863768-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
100% Match
HP 873777-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
100% Match
HP 878677-001 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
100% Match
HP MB010000GWAYN 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
98% Match
HP 857648-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
98% Match
HP 873840-001 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✓ Sector Size: 512e
96% Match
HP 857967-001 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
96% Match
HP 878566-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
96% Match
HP 857653-002 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
96% Match
HP P11184-001 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
96% Match
HP P09161-B21 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
94% Match
HP 857968-001 10TB MidLine SATA 6Gb/s 3.5" LFF 7.2K LPC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
+ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
+ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
+ Dual Port: Yes

Customer Reviews

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2
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1
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G
Gary B.
2025-06-12
✓ Verified Buyer
★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
✓ Verified Buyer
★★★★★
The refurbished drives we ordered were in perfect condition.
M
Mitch F.
2025-04-04
✓ Verified Buyer
★★★★★
BoostHardware always has what I need at reasonable prices.
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David P.
2025-03-28
✓ Verified Buyer
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Delivered on time.
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Louis J.
2025-03-26
✓ Verified Buyer
★★★★★
Found the hard drives I needed. The ordering process was smooth and fast. Got the drives next day.
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Darryl P.
2025-03-25
✓ Verified Buyer
★★★★★
Excellent personal service, thanks Scott!
L
Lindsay M.
2025-03-21
✓ Verified Buyer
★★★★★
Good price on the drives we needed.

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