FREE DELIVERY ANYWHERE IN THE USA
We accept PO’s from qualified businesses, government agencies, defense, and educational institutions.
0
Contact Us
1-888-352-2298 [email protected]
Home / HP / Hard Drives / HP 857646-B21

HP 857646-B21 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K LPC DS Helium 512e HDD

Part Number: 857646-B21     Brand: HP
Free 2-Day
Shipping $99+
857646-B21 HP Image

857646-B21 Price

New Condition · Ready to Ship
$534.00 $543.40
★ 6% Off Applied at Checkout
★ Free US 2-Day Express Shipping Over $99
Condition
Quantity

HP 857646-B21 Specs

▲
Brand
HP
Capacity
10TB
Hot-Swappable
Yes
Spindle Speed
7.2K
Carrier Type
Low Profile Carrier (LPC)
Interface Type
SAS
Data Transfer Rate
12Gb/s
Workload
MidLine (MDL)
Encryption
Digitally Signed (DS)
Sector Size
512e
Form Factor
3.5" LFF
Drive Technology (Fill)
Helium
HPE Server Generations
Gen 9/Gen 11/Gen 10+/Gen 10

This HP Hard Drive 857646-B21 is compatible with these HP Servers

▲
ProLiant DL20
ProLiant DL320
ProLiant DL325
ProLiant DL345
ProLiant DL360
ProLiant DL380
ProLiant DL385
Proliant DL160
Proliant DL180
Proliant ML110
Proliant ML350
Proliant XL170r
Proliant XL190r

HP 857646-B21 Description

▼

The HP 857646-B21 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K LPC DS Helium 512e HDD is a high-capacity, reliable hard drive designed for enterprise storage solutions. Ideal for use in data centers and business-critical applications, this drive supports a wide range of HPE ProLiant server models including ProLiant DX, DL, ML, SL, BL, XL, and CL series. With its large 10TB capacity and efficient helium-filled technology, it offers enhanced storage density and energy efficiency, making it perfect for midline workloads that require a balance of performance and cost-effectiveness.

Key specifications of this drive highlight its robust performance and compatibility. It features a 3.5-inch Large Form Factor (LFF) design with a Low Profile Carrier (LPC) for easy integration into server chassis. The SAS interface supports a fast 12Gb/s data transfer rate, ensuring quick access to stored data. Running at 7,200 RPM spindle speed, it provides reliable performance for midline workloads. Additionally, the drive supports digital signature encryption for data integrity and uses 512e sector size formatting. It is hot-swappable, allowing for easy maintenance without downtime, and is compatible with HPE server generations Gen 9 through Gen 11.

  • Brand: HP
  • Capacity: 10TB
  • Hot-Swappable: Yes
  • Spindle Speed: 7.2K RPM
  • Carrier Type: Low Profile Carrier (LPC)
  • Interface Type: SAS
  • Data Transfer Rate: 12Gb/s
  • Workload: MidLine (MDL)
  • Encryption: Digitally Signed (DS)
  • Sector Size: 512e
  • Form Factor: 3.5" LFF
  • Drive Technology: Helium-filled
  • HPE Server Generations: Gen 9 / Gen 10 / Gen 10+ / Gen 11

For maintenance and replacement purposes, the following spare part numbers correspond to this drive:

Trusted by 5000+ IT Managers, System Integrators & Data Center Experts
Excellent
289 reviews on
Reviews.io

Easy Returns

"We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund."

Even P.

Lowest Price By Far

"We were able to purchase 10x HP 782995-001 for 25% less than the next lowest price. Very impressed with the quick shipping and lack of issues."

Bobbie I

Excellent Customer Service

"Excellent customer service; they got in touch with me right away. They upgraded my next order to free 2-day shipping."

Everett M.
ⓘ We found 18 subs for the HP 857646-B21
100% Match
HP 820032-001 8TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 8TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP P09149-S21 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP P09149-B21 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K LPC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP P11187-001 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP 857644-B21 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP 857965-001 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
100% Match
HP P11186-001 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K LPC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
98% Match
HP 857966-001 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
+ Dual Port: Yes
98% Match
HP MB010000JWAYK 10TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS Helium 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 10TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✓ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
+ Dual Port: Yes
90% Match
HP 846610-001 6TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 6TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
90% Match
HP 846514-B21 6TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 6TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
88% Match
HP 846509-001 6TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 6TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
+ Cache: 128MB
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
88% Match
HP 819199-001 8TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC DS 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 8TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
+ Cache: 128MB
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
81% Match
HP 819201-B21 8TB MidLine SAS 12Gb/s 3.5" LFF 7.2K SC 512e HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 8TB
✓ Interface: SAS
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✕ Hot-Swappable: Yes
✓ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Sector Size: 512e
70% Match
HP 628182-001 3TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 3TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
+ Cache: 64MB
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✕ Encryption: Digitally Signed (DS)
✕ Sector Size: 512e
70% Match
HP 628061-B21 3TB MidLine SATA 6Gb/s 3.5" LFF 7.2K SC HDD
✓ Spindle Speed: 7.2K
✓ Capacity: 3TB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
+ Cache: 64MB
✓ Brand: HP
✓ Workload: MidLine (MDL)
✕ Drive Technology (Fill): Helium
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s
✕ Encryption: Digitally Signed (DS)
✕ Sector Size: 512e
0% Match
HP 718177-B21 240GB SATA 6Gb/s 3.5" LFF Enterprise Value SC MLC SSD
✓ Capacity: 240GB
✓ Interface: SATA
✓ Form Factor: 3.5" LFF
✓ Brand: HP
✓ Workload: Enterprise Value (EV)
✓ NAND Flash Memory Type: Multi-Level Cell (MLC)
✓ Hot-Swappable: Yes
✓ Data Transfer Rate: 6Gb/s

Customer Reviews

4.8
★★★★★
289 reviews
94% recommend
5
(253)
4
(21)
3
(9)
2
(2)
1
(4)
G
Gary B.
2025-06-12
✓ Verified Buyer
★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
✓ Verified Buyer
★★★★★
The refurbished drives we ordered were in perfect condition.
M
Mitch F.
2025-04-04
✓ Verified Buyer
★★★★★
BoostHardware always has what I need at reasonable prices.
D
David P.
2025-03-28
✓ Verified Buyer
★★★★★
Delivered on time.
L
Louis J.
2025-03-26
✓ Verified Buyer
★★★★★
Found the hard drives I needed. The ordering process was smooth and fast. Got the drives next day.
D
Darryl P.
2025-03-25
✓ Verified Buyer
★★★★★
Excellent personal service, thanks Scott!
L
Lindsay M.
2025-03-21
✓ Verified Buyer
★★★★★
Good price on the drives we needed.

Expert Sales Support

Looking for a bulk discount? Call 1-888-352-2298 and a rep will assist you with part no. 857646-B21.

Availability

New Condition: In Stock

Refurbished Condition: In Stock

Delivery Options

Overnight and Express Delivery in USA
Get within 1 to 3 days

$49 Ground Shipping To Canada

International Delivery Options Available
Contact Us For Detail

Payment Options

All Credit Cards Accepted + PayPal

PO Accepted from Qualified Businesses and Government Entities

Return & Warranty

30 days return

Warranty vary by product please see our Policies page