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Home / HP / Solid State Drives / HP P16503-S21

HP P16503-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD

Part Number: P16503-S21     Brand: HP
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Quantity

HP P16503-S21 Product Specs

▲
Brand
HP
Capacity
3.84TB
Workload
Read Intensive (RI)
Encryption
Digitally Signed (DS)
Form Factor
2.5" SFF
Data Transfer Protocol
NVMe
HPE Server Generations
Gen 10+/Gen 10

This HP Solid State Drive P16503-S21 is compatible with these HP Servers

▲
ProLiant DL325
ProLiant DL365
ProLiant DL385
Proliant DL560
Proliant DL580

HP P16503-S21 Description

▼

Introducing the HP P16503-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD, a high-performance storage solution designed to meet the demands of enterprise environments. This SSD is ideal for read-intensive workloads such as database querying, virtualization, and web serving. It is fully compatible with a wide range of HPE ProLiant servers including the ProLiant DX, DL, ML, SL, BL, XL, and CL series, making it a versatile choice for data centers and IT infrastructures running Gen 10 and later server generations.

Key specifications of the HP P16503-S21 SSD emphasize its robust performance and security features. With a large 3.84TB capacity, this solid-state drive offers ample space for critical data storage. Utilizing the PCIe NVMe interface, it delivers fast data transfer speeds and low latency, perfect for accelerating read-intensive applications. The 2.5" Small Form Factor (SFF) ensures easy integration into existing server bays. Additionally, the drive incorporates digital signature encryption (DS) to safeguard data integrity and prevent unauthorized firmware modifications.

  • Brand: HP
  • Capacity: 3.84TB
  • Workload Type: Read Intensive (RI)
  • Encryption: Digitally Signed (DS)
  • Form Factor: 2.5" Small Form Factor (SFF)
  • Data Transfer Protocol: NVMe
  • Compatible Server Generations: HPE Gen 10+ / Gen 10
  • Compatible Server Models: ProLiant DX, DL, ML, SL, BL, XL, CL

For maintenance and replacement purposes, the following spare part numbers correspond to this SSD model:

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ⓘ We found 47 subs for the HP P16503-S21
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HP P20019-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: IDE
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
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HP P20019-B21 3.84TB PCIe NVMe U.3 2.5" SFF Read Intensive SC DS SSD
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✓ Form Factor: 2.5" SFF
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✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P20141-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P13680-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
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✓ Encryption: Digitally Signed (DS)
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HP P10216-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
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HP P50217-B21 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
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✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
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HP P07194-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
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HP P10212-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P50218-B21 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P19817-S21 3.84TB PCIe NVMe 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P50956-001 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P50219-B21 3.84TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: IDE
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P20614-001 3.84TB PCIe NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
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✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
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✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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+ Interface: PCIe 4.0
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✓ Brand: HP
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✓ Encryption: Digitally Signed (DS)
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✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
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✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
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+ Interface: PCIe
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✓ Brand: HP
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+ Data Transfer Lanes: x4
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✓ Capacity: 3.84TB
+ Interface: PCIe
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✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
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+ Interface: PCIe
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✓ Brand: HP
✓ Workload: Read Intensive (RI)
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✓ Encryption: Digitally Signed (DS)
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+ Drive Interface: U.3
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HP P41564-001 3.84TB PCIe 4.0 6Gb/s x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: SATA
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Data Transfer Rate: 6Gb/s
✓ Encryption: Digitally Signed (DS)
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+ Drive Interface: U.3
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+ Interface: IDE
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✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P20615-001 3.84TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P20803-001 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
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✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P19815-B21 3.84TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Data Transfer Rate: 6Gb/s
✓ Encryption: Digitally Signed (DS)
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+ Drive Interface: U.3
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✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP P13680-B21 3.84TB PCIe x4 NVMe U.2 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
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HP P20133-B21 3.84TB IDE NVMe U.3 2.5" SFF Read Intensive TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
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HP VO003840KWVMU 3.84TB PCIe x4 NVMe 2.5" SFF Read Intensive MLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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HP P44580-B21 3.84TB PCIe NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
92% Match
HP VO003840JWDAV 3.84TB SAS 12Gb/s 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: SAS
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
92% Match
HP P22278-B21 3.84TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
92% Match
HP P07194-B21 3.84TB PCIe x4 NVMe 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
92% Match
HP 872396-005 3.84TB SAS 12Gb/s 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 3.84TB
+ Interface: SAS
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Hot-Swappable: Yes
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
92% Match
HP 872394-B21 3.84TB SAS 12Gb/s 2.5" SFF Read Intensive SC MLC DS SSD
✓ Capacity: 3.84TB
+ Interface: SAS
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Hot-Swappable: Yes
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Protocol: NVMe
90% Match
HP P10212-B21 3.84TB PCIe x4 NVMe 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
90% Match
HP P10467-001 3.84TB PCIe x4 NVMe U.2 2.5" SFF Read Intensive SC MLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
90% Match
HP P09769-002 3.84TB PCIe x4 NVMe U.2 2.5" SFF Read Intensive SC MLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
90% Match
HP P10654-001 3.84TB PCIe x4 NVMe U.2 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Encryption: Digitally Signed (DS)
+ Sector Size: 512e
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
90% Match
HP P48225-001 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive TLC DS SSD
✓ Capacity: 3.84TB
+ Interface: IDE
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
90% Match
HP P40566-B21 3.84TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
+ Spindle Speed: 10K
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3
90% Match
HP P52325-001 3.84TB PCIe 4.0 x4 NVMe U.2 2.5" SFF Read Intensive DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
88% Match
HP P10216-B21 3.84TB PCIe x4 NVMe U.2 2.5" SFF Read Intensive SC MLC DS SSD
✓ Capacity: 3.84TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
+ Dual Port: Yes
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.2
88% Match
HP P16503-B21 3.84TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
+ Spindle Speed: 10K
✓ Capacity: 3.84TB
+ Interface: SAS
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Data Transfer Rate: 24Gb/s
✓ Encryption: Digitally Signed (DS)
+ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
+ Drive Interface: U.3

Customer Reviews

4.8
★★★★★
289 reviews
94% recommend
5
(253)
4
(21)
3
(9)
2
(2)
1
(4)
G
Gary B.
2025-06-12
✓ Verified Buyer
★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
✓ Verified Buyer
★★★★★
The refurbished drives we ordered were in perfect condition.
M
Mitch F.
2025-04-04
✓ Verified Buyer
★★★★★
BoostHardware always has what I need at reasonable prices.
D
David P.
2025-03-28
✓ Verified Buyer
★★★★★
Delivered on time.
L
Louis J.
2025-03-26
✓ Verified Buyer
★★★★★
Found the hard drives I needed. The ordering process was smooth and fast. Got the drives next day.
D
Darryl P.
2025-03-25
✓ Verified Buyer
★★★★★
Excellent personal service, thanks Scott!
L
Lindsay M.
2025-03-21
✓ Verified Buyer
★★★★★
Good price on the drives we needed.

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