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Home / HP / Solid State Drives / HP P16499-S21

HP P16499-S21 1.6TB PCIe NVMe 2.5" SFF Mixed Use DS SSD

Part Number: P16499-S21     Brand: HP
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Quantity

HP P16499-S21 Product Specs

▲
Brand
HP
Capacity
3.2TB
Carrier Type
Smart Carrier (SC)
Interface Type
PCIe
Workload
Mixed Use (MU)
Encryption
Digitally Signed (DS)
Form Factor
2.5" SFF
Drive Interface
U.3
Data Transfer Lanes
x4
Data Transfer Protocol
NVMe
HPE Server Generations
Gen 10+/Gen 10

This HP Solid State Drive P16499-S21 is compatible with these HP Servers

▲
ProLiant DL325
ProLiant DL365
ProLiant DL385
Proliant DL560
Proliant DL580

HP P16499-S21 Description

▼

Introducing the HP P16499-S21 1.6TB PCIe NVMe 2.5" SFF Mixed Use DS SSD, a high-performance storage solution designed to enhance your server's speed and reliability. Ideal for enterprise environments, this SSD is compatible with a wide range of HPE ProLiant server models including ProLiant DX, DL, ML, SL, BL, XL, and CL series. Whether you're running demanding applications, virtualization, or data-intensive workloads, this solid-state drive delivers fast data access and robust endurance to keep your systems running smoothly.

Let's take a closer look at the key specifications that make this SSD a standout choice for mixed-use workloads:

  • Brand: HP – trusted for quality and reliability in enterprise storage
  • Capacity: 3.2TB, providing ample space for large datasets and applications
  • Carrier Type: Smart Carrier (SC), ensuring easy installation and compatibility
  • Interface Type: PCIe, enabling ultra-fast data transfer speeds
  • Workload: Mixed Use (MU), optimized for a blend of read and write operations
  • Encryption: Digitally Signed (DS), enhancing data security and integrity
  • Form Factor: 2.5" Small Form Factor (SFF), fitting standard server bays
  • Drive Interface: U.3, supporting hot-swappable capabilities and broad compatibility
  • Data Transfer Lanes: x4 lanes, maximizing throughput
  • Data Transfer Protocol: NVMe, delivering low latency and high IOPS performance
  • HPE Server Generations: Compatible with Gen 10+ and Gen 10 servers

For maintenance and replacement, consider the following spare part numbers compatible with this SSD:

Upgrade your HPE ProLiant servers with the HP P16499-S21 SSD to experience faster boot times, improved application responsiveness, and reliable mixed-use performance tailored for enterprise demands.

Trusted by 5000+ IT Managers, System Integrators & Data Center Experts
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289 reviews on
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"We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund."

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Everett M.
ⓘ We found 8 subs for the HP P16499-S21
100% Match
HP P20098-B21 3.2TB PCIe NVMe U.3 2.5" SFF Mixed Use DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
100% Match
HP P19833-B21 3.2TB PCIe NVMe U.3 2.5" SFF Mixed Use MLC DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
100% Match
HP P20795-001 3.2TB PCIe NVMe U.3 2.5" SFF Mixed Use DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
100% Match
HP P22270-S21 3.2TB PCIe x4 NVMe U.3 2.5" SFF Mixed Use DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
100% Match
HP P20088-B21 1.6TB PCIe NVMe U.3 2.5" SFF Mixed Use DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
98% Match
HP P22270-B21 3.2TB PCIe x4 NVMe U.3 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
98% Match
HP P26415-001 3.2TB PCIe x4 NVMe U.3 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
96% Match
HP P47835-B21 3.2TB PCIe NVMe U.3 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 3.2TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Data Transfer Rate: 6Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3

Customer Reviews

4.8
★★★★★
289 reviews
94% recommend
5
(253)
4
(21)
3
(9)
2
(2)
1
(4)
G
Gary B.
2025-06-12
✓ Verified Buyer
★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
✓ Verified Buyer
★★★★★
The refurbished drives we ordered were in perfect condition.
M
Mitch F.
2025-04-04
✓ Verified Buyer
★★★★★
BoostHardware always has what I need at reasonable prices.
D
David P.
2025-03-28
✓ Verified Buyer
★★★★★
Delivered on time.
L
Louis J.
2025-03-26
✓ Verified Buyer
★★★★★
Found the hard drives I needed. The ordering process was smooth and fast. Got the drives next day.
D
Darryl P.
2025-03-25
✓ Verified Buyer
★★★★★
Excellent personal service, thanks Scott!
L
Lindsay M.
2025-03-21
✓ Verified Buyer
★★★★★
Good price on the drives we needed.

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