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Home / HP / Solid State Drives / HP P22280-S21

HP P22280-S21 7.68TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive DS SSD

Part Number: P22280-S21     Brand: HP
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P22280-S21 HP Image

P22280-S21 Price

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$2,269.00 $2,295.95
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Condition
Quantity

HP P22280-S21 Specs

▲
Brand
HP
Capacity
7.68TB
Workload
Read Intensive (RI)
Encryption
Digitally Signed (DS)
Form Factor
2.5" SFF
Drive Interface
U.3
Data Transfer Lanes
x4
Data Transfer Protocol
NVMe
HPE Server Generations
Gen 10+/Gen 10

This HP Solid State Drive P22280-S21 is compatible with these HP Servers

▲
ProLiant DL365
Proliant DL360
Proliant DL560
Proliant DL580

HP P22280-S21 Description

▼

The HP P22280-S21 7.68TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive DS SSD is a high-performance solid-state drive designed to meet the demanding storage needs of modern enterprise environments. Ideal for data centers and servers, this SSD is compatible with a wide range of HPE ProLiant server models including ProLiant DX, DL, ML, SL, BL, XL, and CL series. It supports Gen 10 and Gen 10+ HPE server generations, ensuring seamless integration and reliable performance for applications requiring fast read speeds and consistent data access.

This SSD is particularly suited for read-intensive workloads, making it an excellent choice for database servers, virtualization, and cloud computing environments where quick data retrieval is critical. Featuring a compact 2.5" Small Form Factor (SFF) with a U.3 interface, it leverages PCIe x4 lanes and NVMe protocol to deliver ultra-low latency and high throughput.

Key specifications of the HP P22280-S21 SSD include:

  • Brand: HP
  • Capacity: 7.68TB, providing ample storage for large datasets
  • Workload: Read Intensive (RI), optimized for frequent read operations
  • Encryption: Digitally Signed (DS) for enhanced data security and integrity
  • Form Factor: 2.5" Small Form Factor (SFF), suitable for dense server configurations
  • Drive Interface: U.3, supporting hot-plug capability and backward compatibility
  • Data Transfer Lanes: PCIe x4, enabling high-speed data transfer
  • Data Transfer Protocol: NVMe, designed for fast and efficient SSD communication
  • HPE Server Generations: Compatible with Gen 10 and Gen 10+ servers

For maintenance and replacement, the following spare part numbers correspond to this SSD model:

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ⓘ We found 10 subs for the HP P22280-S21
98% Match
HP P19821-B21 7.68TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
98% Match
HP P19819-B21 7.68TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
98% Match
HP P26420-001 7.68TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
98% Match
HP P20605-001 7.68TB PCIe 4.0 x4 NVMe U.3 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
96% Match
HP P20143-B21 7.68TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
96% Match
HP P20804-001 7.68TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive SC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
96% Match
HP P26104-B21 7.68TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
94% Match
HP P50222-B21 7.68TB PCIe 4.0 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 7.68TB
+ Interface: IDE
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
94% Match
HP P40567-B21 7.68TB PCIe x4 NVMe U.3 2.5" SFF Read Intensive DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe 4.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Triple-Level Cell (TLC)
+ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
94% Match
HP P10468-001 7.68TB PCIe 12Gb/s x4 NVMe U.2 2.5" SFF Read Intensive SC TLC DS SSD
✓ Capacity: 7.68TB
+ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Read Intensive (RI)
+ NAND Flash Memory Type: Multi-Level Cell (MLC)
+ Data Transfer Rate: 12Gb/s
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3

Customer Reviews

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Gary B.
2025-06-12
✓ Verified Buyer
★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
✓ Verified Buyer
★★★★★
The refurbished drives we ordered were in perfect condition.
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Mitch F.
2025-04-04
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BoostHardware always has what I need at reasonable prices.
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2025-03-28
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Delivered on time.
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2025-03-26
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Found the hard drives I needed. The ordering process was smooth and fast. Got the drives next day.
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Darryl P.
2025-03-25
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Excellent personal service, thanks Scott!
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Lindsay M.
2025-03-21
✓ Verified Buyer
★★★★★
Good price on the drives we needed.

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