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Home / HP / Solid State Drives / HP P22272-B21

HP P22272-B21 6.4TB PCIe x4 NVMe U.3 2.5" SFF Mixed Use SC TLC DS SSD

Part Number: P22272-B21     Brand: HP
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P22272-B21 Price

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Condition
Quantity

HP P22272-B21 Specs

▲
Brand
HP
Capacity
6.4TB
Hot-Swappable
Yes
Carrier Type
Smart Carrier (SC)
Interface Type
PCIe
Workload
Mixed Use (MU)
Encryption
Digitally Signed (DS)
NAND Flash Memory Type
Triple-Level Cell (TLC)
Form Factor
2.5" SFF
Drive Interface
U.3
Data Transfer Lanes
x4
Data Transfer Protocol
NVMe
HPE Server Generations
Gen 10+/Gen 10

This HP Solid State Drive P22272-B21 is compatible with these HP Servers

▲
ProLiant DL365
Proliant DL360
Proliant DL560
Proliant DL580

HP P22272-B21 Description

▼

The HP P22272-B21 6.4TB PCIe x4 NVMe U.3 2.5" SFF Mixed Use SC TLC DS SSD is a high-performance solid-state drive designed to enhance storage capabilities in a variety of HPE ProLiant servers. Ideal for mixed-use workloads, this SSD offers a perfect balance of speed, capacity, and reliability, making it suitable for data-intensive applications such as virtualization, database management, and cloud computing. It is compatible with multiple HPE ProLiant server models, including ProLiant DX, DL, ML, SL, BL, XL, and CL series, ensuring broad support across your enterprise infrastructure.

This SSD boasts impressive specifications that cater to demanding enterprise environments. Its 6.4TB capacity provides ample storage space, while the PCIe interface with NVMe protocol and x4 data transfer lanes deliver exceptional data throughput and low latency. The drive's 2.5" small form factor (SFF) with U.3 interface supports hot-swappable capabilities, allowing for easy maintenance and upgrades without downtime. Additionally, the Smart Carrier (SC) design enhances drive management and security, complemented by digitally signed encryption for data integrity. Built with Triple-Level Cell (TLC) NAND flash memory, this SSD balances endurance and cost-effectiveness, optimized for mixed-use workloads in HPE Gen 10 and Gen 10+ server generations.

  • Brand: HP
  • Capacity: 6.4TB
  • Hot-Swappable: Yes
  • Carrier Type: Smart Carrier (SC)
  • Interface Type: PCIe
  • Workload: Mixed Use (MU)
  • Encryption: Digitally Signed (DS)
  • NAND Flash Memory Type: Triple-Level Cell (TLC)
  • Form Factor: 2.5" Small Form Factor (SFF)
  • Drive Interface: U.3
  • Data Transfer Lanes: x4
  • Data Transfer Protocol: NVMe
  • HPE Server Generations: Gen 10+ / Gen 10

For maintenance or replacement, the following spare part numbers are available for this SSD:

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ⓘ We found 13 subs for the HP P22272-B21
100% Match
HP P10222-B21 1.6TB PCIe x4 NVMe 2.5" SFF Mixed Use SC MLC DS SSD
✓ Capacity: 1.6TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ NAND Flash Memory Type: Multi-Level Cell (MLC)
✓ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
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HP P13674-B21 6.4TB PCIe x4 NVMe U.2 2.5" SFF Mixed Use SC TLC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
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HP P10226-B21 6.4TB PCIe x4 NVMe U.2 2.5" SFF Mixed Use SC MLC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ NAND Flash Memory Type: Multi-Level Cell (MLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
90% Match
HP P10472-001 6.4TB PCIe x4 NVMe U.2 2.5" SFF Mixed Use SC MLC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ NAND Flash Memory Type: Multi-Level Cell (MLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
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HP P10651-001 6.4TB PCIe 3.0 x4 NVMe U.2 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe 3.0
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✓ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
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✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
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HP P13703-B21 6.4TB PCIe x4 NVMe U.2 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
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✓ Capacity: 6.4TB
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✓ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.2
✕ Interface: PCIe
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HP P19837-B21 6.4TB PCIe NVMe U.3 2.5" SFF Mixed Use SC DS SSD
✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✓ Hot-Swappable: Yes
+ Data Transfer Rate: 6Gb/s
✓ Encryption: Digitally Signed (DS)
✕ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Drive Interface: U.3
✕ Hot-Swappable: Yes
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✓ Data Transfer Lanes: x4
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✓ Capacity: 6.4TB
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✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Hot-Swappable: Yes
✓ Encryption: Digitally Signed (DS)
✕ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
✓ Drive Interface: U.3
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✓ Capacity: 6.4TB
✓ Interface: PCIe
✓ Form Factor: 2.5" SFF
✓ Brand: HP
✓ Workload: Mixed Use (MU)
✕ NAND Flash Memory Type: Triple-Level Cell (TLC)
✕ Hot-Swappable: Yes
+ Data Transfer Rate: 6Gb/s
✓ Encryption: Digitally Signed (DS)
✕ Data Transfer Lanes: x4
✓ Data Transfer Protocol: NVMe
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Customer Reviews

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Gary B.
2025-06-12
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★★★★★
The sales guy at Boost Hardware was super knowledgeable. He helped me find the right part for my older Proliant server.
E
Even P.
2025-04-09
✓ Verified Buyer
★★★★★
We purchased the wrong part by mistake. Boost hardware made it easy to return and quickly issued me a refund.
M
Matthew S.
2025-04-08
✓ Verified Buyer
★★★★★
Good purchasing experience.
A
Aaron P.
2025-04-04
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★★★★★
The refurbished drives we ordered were in perfect condition.
M
Mitch F.
2025-04-04
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BoostHardware always has what I need at reasonable prices.
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2025-03-28
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2025-03-26
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2025-03-25
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Lindsay M.
2025-03-21
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★★★★★
Good price on the drives we needed.

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